SAB4502683

Anti-p70 S6 Kinase antibody produced in rabbit

affinity isolated antibody

• 동의어(들): 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, S6K, S6K1, p70 S6 kinase α
• MDL number: MFCD01092452
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 59 kDa
• 종 반응성: rat, human, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P23443
• UniProt 수납 번호: P23443
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... RPS6KB1(6198)

설명

일반 설명

Ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) belongs to the AGC kinase subfamily and comprises a catalytic domain, a linker region, and a putative autoinhibitory domain, in addition to the N-terminal and C-terminal domain. The RPS6KB1 gene is located on human chromosome 17q23.1. It exists in multiple isoforms due to alternative splice events.

면역원

The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase.

Immunogen Range: 195-244

애플리케이션

Anti-p70 S6 Kinase antibody produced in rabbit has been used in western blotting (1:1000).

생화학적/생리학적 작용

Ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1) undergoes acetylation, phosphorylation, and ubiquitination. It is involved in a variety of functions including glucose homeostasis, cell survival, and proliferation. RPS6KB1 also participates in cell structure and organization. It is implicated in ovarian cancer progression, muscle hypertrophy, aging, immunity, and memory. RPS6KB1 also regulates the replication and transcription of mumps virus (MuV).

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable