추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 52 kDa
종 반응성
rat, human, mouse
농도
~1 mg/mL
기술
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CCNA1(8900)
일반 설명
Anti-Cyclin A Antibody detects endogenous levels of total Cyclin A protein.
CCNA1 (cyclin A1) is a member of the highly conserved cyclin family. There are two A-type cyclins, namely cyclin A1 and cyclin A2. Cyclin A1 is expressed at high levels in testis and expressed at low levels in most other tissues. This gene is mapped to human chromosome 13q13.
면역원
The antiserum was produced against synthesized peptide derived from human Cyclin A.
Immunogen Range: 221-270
Immunogen Range: 221-270
애플리케이션
Anti-Cyclin A antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
생화학적/생리학적 작용
CCNA1 (cyclin A1) controls cell apoptosis. Cyclin A2 is required for DNA replication and proliferation in somatic cells. CCNA1 plays an important role in head and neck carcinoma and cervical and nasopharyngeal cancers.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Correlation of CCNA1 promoter methylation with malignant tumors: a meta-analysis introduction.
Yang B, et al.
BioMed Research International, 2015, 134027-134027 (2015)
Cyclin A1 shows age-related expression in benign tonsils, HPV16-dependent overexpression in HNSCC and predicts lower recurrence rate in HNSCC independently of HPV16.
Weiss D, et al.
BMC Cancer, 12(1), 259-259 (2012)
Xiaomin Su et al.
BMC developmental biology, 20(1), 22-22 (2020-11-19)
Tissue regeneration mediated by mesenchymal stem cells (MSCs) is deemed a desirable way to repair teeth and craniomaxillofacial tissue defects. Nevertheless, the molecular mechanisms about cell proliferation and committed differentiation of MSCs remain obscure. Previous researches have proved that lysine
Depletion of HOXA5 inhibits the osteogenic differentiation and proliferation potential of stem cells from the apical papilla.
Li W, et al.
Cell Biology International, 42(1), 45-52 (2018)
Wenzhi Li et al.
Cell biology international, 42(1), 45-52 (2017-08-24)
Mesenchymal stem cells (MSCs) are a prospective cell source for tissue regeneration due to their self-renewal abilities and potential to differentiate into different cell lineages, but the molecular mechanisms of the directed differentiation and proliferation are still unknown. Recently, multiple
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