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Merck
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Key Documents

T6442

Sigma-Aldrich

Anti-TRPC6 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

동의어(들):

Anti-Transient receptor potential cation channel, subfamily C, member 6 antibody produced in rabbit

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

lyophilized powder

종 반응성

mouse, rat

기술

immunohistochemistry: suitable using mouse brain sections
western blot: 1:200-1:400 using rat brain or lung lysates

UniProt 수납 번호

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... TRPC6(7225)
mouse ... Trpc6(22068)
rat ... Trpc6(89823)

면역원

synthetic peptide (RRNESQDYLLMDELG) corresponding to amino acids residues 24-38 of mouse TRPC6. This sequence is identical in rat and highly homologous (15/16 residues identical) in human.

물리적 형태

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Yonghong Bai et al.
eLife, 9 (2020-03-10)
Transient receptor potential canonical (TRPC) proteins form nonselective cation channels that play physiological roles in a wide variety of cells. Despite growing evidence supporting the therapeutic potential of TRPC6 inhibition in treating pathological cardiac and renal conditions, mechanistic understanding of
Chengkang He et al.
JCI insight, 7(5) (2022-01-26)
Currently, the most effective strategy for dealing with Alzheimer's disease (AD) is delaying the onset of dementia. Severe hypoglycemia is strongly associated with dementia; however, the effects of recurrent moderate hypoglycemia (RH) on the progression of cognitive deficits in patients
Yanna Du et al.
Molecular medicine reports, 16(2), 1117-1124 (2017-06-20)
Persistent pulmonary hypertension of the newborn (PPHN) is a life‑threatening disease that is commonly observed in the neonatal intensive care unit. PPHN is pathologically characterized by pulmonary vascular remodeling and, in particular, pulmonary artery smooth muscle cell (PASMC) proliferation. Decreased
Ying Meng et al.
International journal of molecular medicine, 37(1), 258-266 (2016-01-01)
Ischemia-reperfusion (I/R) plays an important role in myocardial injury. In the present study, we aimed to examine the protective effects of Danshensu (DSS) against I/R injury and to elucidate the underlying mechanisms. For this purpose, H9c2 cells were cultured in hypoxic solution
M Salomonsson et al.
Acta physiologica (Oxford, England), 200(3), 265-278 (2010-04-30)
In rat afferent arterioles we investigated the role of Na(+) entry in noradrenaline (NA)-induced depolarization and voltage-dependent Ca(2+) entry together with the importance of the transient receptor potential channel (TRPC) subfamily for non-voltage-dependent Ca(2+) entry. R (340/380) Fura-2 fluorescence was

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