1297001

Human chorionic gonadotropin

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): Chorionic gonadotropin human, Choriogonin, HCG
• CAS Number: 9002-61-3
• MDL number: MFCD00130797
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: gonadotropin
• 분자량: 37.9 kDa
• 제조업체/상표: USP
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: −20°C

설명

일반 설명

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

• Comprehensive Prenatal Screening: Human chorionic gonadotropin (hCG) is crucial in combined first-trimester screening and invasive diagnostics for chromosomal aberrations, offering insights into prenatal health and improving detection rates compared with non-invasive prenatal testing (NIPT). This underscores hCG′s vital role in early gestational health assessments (Gadsbøll et al., 2024).


• Twin Pregnancy Outcomes: hCG levels are studied for their association with adverse outcomes in twin gestations, providing valuable data for managing and monitoring high-risk pregnancies. This research highlights hCG′s predictive value in obstetrics, aiding in the anticipatory management of potential complications (Yamasato and Ono, 2024).


• Missed Abortion Treatment: The effectiveness of Nigella sativa oil, influenced by hCG levels, on the outcomes of missed abortions is explored through a randomized clinical trial. This study demonstrates the potential for integrating hCG monitoring into therapeutic strategies to improve pregnancy outcomes (Mohammadi et al., 2024).


• Germ Cell Testicular Tumor Biomarkers: The role of hCG as a biomarker in germ cell testicular tumors is examined, enhancing the understanding of tumor biology and improving diagnostic accuracy. This research is pivotal for developing targeted therapies and improving prognostic evaluations in oncology (Kılınç et al., 2024).


• Molar Cesarean Scar Ectopic Pregnancy: Studies involving hCG focus on its implications in rare cases of molar cesarean scar ectopic pregnancies, providing insights into unusual gestational complications. This research is crucial for developing guidelines and treatment protocols in exceptionally complex pregnancy cases (Hosseinimousa et al., 2024).

포장

1 vial, 530 USP units per package

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

This product is part of the USP Biologics program.

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS08
• 신호어: Warning
• 유해 및 위험 성명서: H361
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable