- How water links to cis and trans peptidic groups: the rotational spectrum of N-methylformamide-water.
How water links to cis and trans peptidic groups: the rotational spectrum of N-methylformamide-water.
Physical chemistry chemical physics : PCCP (2010-07-27)
Walther Caminati, Juan Carlos López, Susana Blanco, Santiago Mata, Josè Luis Alonso
PMID20657893
초록
We investigated the Fourier transform microwave spectra of the hydrated forms of N-methylformamide (NMF) in a supersonic expansion and assigned the rotational spectra of two mono-hydrated species. The conformation of each molecular complex was reliably determined on the basis of the values of the rotational constants, of the relative intensities of mu(a)- and mu(b)-type transitions, and of the features of the (14)N quadrupole hyperfine structure of the rotational transitions. In both complexes water acts as a proton donor and NMF has a trans configuration of the peptidic group. In the most stable of these conformers, water is also weakly bound to the methyl group.
MATERIALS