MilliporeSigma

CCR2

chemokine (C-C motif) receptor 2

Synonyms:
CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Species:
UniProtKB ID:
Gene ID:
  • Human(729230) Summary: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
  • Mouse(12772) chemokine (C-C motif) receptor 2
  • Rat(60463) chemokine (C-C motif) receptor 2
  • domestic guinea pig(100718888) chemokine (C-C motif) receptor 2
  • naked mole-rat(101724105) chemokine (C-C motif) receptor 2
  • Horse(100048936) chemokine (C-C motif) receptor 2
  • cow(539002) chemokine (C-C motif) receptor 2
  • sheep(101117706) chemokine (C-C motif) receptor 2
  • domestic cat(100049057) chemokine (C-C motif) receptor 2
  • Thale Cress(816705) glycine-rich RNA-binding protein 7
  • Thale Cress(818503) serine/threonine-protein kinase-like protein CCR2
  • Thale Cress(844421) cinnamoyl-CoA reductase
  • chicken(420696) chemokine (C-C motif) receptor 2
  • dog(484790) chemokine (C-C motif) receptor 2

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
Boc-Gln-OH, 98%,
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CCR2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-CCR2/CKR2 Antibody, clone 10L1L6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-CCR2 Antibody, clone 8C3.1, clone 8C3.1, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
D-Glutamic acid, ≥99% (TLC),
Species
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

Proteins

Product Number
Description
Species
ChemiSCREEN CCR2B Membrane Preparation, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCR2,
Species
human