MilliporeSigma

FBXO18

F-box protein, helicase, 18

Synonyms:
FBH1, Fbx18
Species:
UniProtKB ID:
Gene ID:
  • Human(84893) Summary: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(50755) F-box protein 18
  • Rat(291293) F-box protein, helicase, 18
  • domestic cat(101099563) F-box protein, helicase, 18
  • sheep(101112918) F-box protein, helicase, 18
  • naked mole-rat(101719984) F-box protein, helicase, 18
  • Horse(100070322) F-box protein, helicase, 18
  • chicken(416687) F-box protein, helicase, 18
  • Zebrafish(567995) F-box protein, helicase, 18
  • dog(487142) F-box protein, helicase, 18
  • cow(534383) F-box protein, helicase, 18
  • domestic guinea pig(100715614) F-box protein, helicase, 18

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXO18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
PrEST Antigen FBXO18, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FBXO18,
Species
human
MISSION® esiRNA, targeting mouse Fbxo18,
Species
mouse