MilliporeSigma

GRIA1

glutamate receptor, ionotropic, AMPA 1

Synonyms:
GLUH1, GLUR1, GLURA, GluA1, HBGR1
Species:
UniProtKB ID:
Gene ID:
  • Human(2890) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14799) glutamate receptor, ionotropic, AMPA1 (alpha 1)
  • Rat(50592) glutamate receptor, ionotropic, AMPA 1
  • dog(489168) glutamate receptor, ionotropic, AMPA 1
  • domestic cat(101097621) glutamate receptor, ionotropic, AMPA 1
  • naked mole-rat(101724828) glutamate receptor, ionotropic, AMPA 1
  • domestic guinea pig(100727046) glutamate receptor, ionotropic, AMPA 1
  • sheep(443271) glutamate receptor, ionotropic, AMPA 1
  • Domestic Rabbit(100348217) glutamate receptor, ionotropic, AMPA 1
  • chicken(414893) glutamate receptor, ionotropic, AMPA 1
  • Horse(100060020) glutamate receptor, ionotropic, AMPA 1
  • cow(529618) glutamate receptor, ionotropic, AMPA 1

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Small Molecule - Agonist

Product Number
Description
Species
ATPA, solid,
Species
human, rat
2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide, ≥98% (HPLC), solid,
Species
human
Quisqualic acid, powder,
Species
rat
Cyclothiazide, ,
Species
human, rat
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Species
human, rat

Small Molecule - Allosteric Modulator

Product Number
Description
Species
CX546, ≥98% (HPLC), solid,
Species
human
Piracetam, ,
Species
human, rat
Cyclothiazide, ,
Species
human, rat
Diazoxide, ,
Species
rat, mouse, human
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
2,3-Pyridinedicarboxylic acid, 99%,
Species
rat
2,3-Dihydroxyquinoxaline, 98%,
Species
rat
GYKI 52466 hydrochloride, solid,
Species
human
ATPA, solid,
Species
human, rat
Piracetam, ,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GRIA1 (Ab-849) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-Glua1/Glur1 - Rpe antibody produced in mouse, clone S355-1, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Glutamate Receptor 1 Antibody, phosphoSer 845, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Glutamate Receptor 1 Antibody, phosphoSer 831, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Cyclothiazide, ,
Species
human, rat
Kynurenic acid, ≥98%,
Species
rat, human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Topiramate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Quisqualic acid, powder,
Species
rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
ATPA, solid,
Species
human, rat
Cyclothiazide, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRIA1,
Species
human