MilliporeSigma

KCNA10

potassium voltage-gated channel, shaker-related subfamily, member 10

Synonyms:
Kcn1, Kv1.8
Species:
UniProtKB ID:
Gene ID:
  • Human(3744) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(242151) potassium voltage-gated channel, shaker-related subfamily, member 10
  • Rat(295360) potassium voltage-gated channel, shaker-related subfamily, member 10
  • cow(538721) potassium voltage-gated channel, shaker-related subfamily, member 10
  • domestic cat(101083609) potassium voltage-gated channel, shaker-related subfamily, member 10
  • dog(490111) potassium voltage-gated channel, shaker-related subfamily, member 10
  • chicken(395116) potassium voltage-gated channel, shaker-related subfamily, member 10
  • naked mole-rat(101716990) potassium voltage-gated channel, shaker-related subfamily, member 10
  • domestic guinea pig(100735330) potassium voltage-gated channel, shaker-related subfamily, member 10
  • sheep(101111758) potassium voltage-gated channel, shaker-related subfamily, member 10

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KCNA10 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
Species
human
Guanidine hydrochloride, ,
Species
human
Guanidine hydrochloride, ≥98%,
Species
human
Dalfampridine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Guanidine hydrochloride, ≥99.0% (AT),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KCNA10,
Species
human