MilliporeSigma

KCNA4

potassium voltage-gated channel, shaker-related subfamily, member 4

Synonyms:
HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2
Species:
UniProtKB ID:
Gene ID:
  • Human(3739) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]
  • Mouse(16492) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Rat(25469) potassium voltage-gated channel, shaker-related subfamily, member 4
  • cow(281880) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic cat(101084479) potassium voltage-gated channel, shaker-related subfamily, member 4
  • dog(485427) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Zebrafish(559036) potassium voltage-gated channel, shaker-related subfamily, member 4
  • chicken(395721) potassium voltage-gated channel, shaker-related subfamily, member 4
  • naked mole-rat(101706863) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic guinea pig(100725985) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Domestic Rabbit(100328568) potassium voltage-gated channel, shaker-related subfamily, member 4
  • sheep(101118217) potassium voltage-gated channel, shaker-related subfamily, member 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-KCNA4 antibody produced in mouse, clone S13-31, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-KCNA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Potassium Channel Kv1.4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
Guanidine hydrochloride, BioUltra, for molecular biology, ≥99.5% (AT),
Species
human
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
Species
human
Guanidine hydrochloride, ,
Species
human
Guanidine hydrochloride, ≥99.0% (AT),
Species
human
Guanidine hydrochloride, ≥99% (titration), organic base and chaeotropic agent,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kcna4,
Species
mouse
MISSION® esiRNA, targeting human KCNA4,
Species
human