MilliporeSigma

KCND2

potassium voltage-gated channel, Shal-related subfamily, member 2

Synonyms:
KV4.2, RK5
Species:
UniProtKB ID:
Gene ID:
  • Human(3751) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq, Jul 2008]
  • Mouse(16508) potassium voltage-gated channel, Shal-related family, member 2
  • Rat(65180) potassium voltage-gated channel, Shal-related subfamily, member 2
  • sheep(101122690) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Domestic Rabbit(100008841) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic guinea pig(100720728) potassium voltage-gated channel, Shal-related subfamily, member 2
  • naked mole-rat(101712898) potassium voltage-gated channel, Shal-related subfamily, member 2
  • chicken(374143) potassium voltage-gated channel, Shal-related subfamily, member 2
  • Zebrafish(570188) potassium voltage-gated channel, Shal-related subfamily, member 2
  • dog(491424) potassium voltage-gated channel, Shal-related subfamily, member 2
  • domestic cat(101093262) potassium voltage-gated channel, Shal-related subfamily, member 2
  • cow(540416) potassium voltage-gated channel, Shal-related subfamily, member 2

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KCND2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KCND2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-Potassium Channel Kv4.2 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
Species
human
Guanidine hydrochloride, ,
Species
human
Guanidine hydrochloride, ≥98%,
Species
human
Dalfampridine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Guanidine hydrochloride, ≥99.0% (AT),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kcnd2,
Species
mouse
MISSION® esiRNA, targeting human KCND2,
Species
human