MilliporeSigma

KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

Synonyms:
EAG, EAG1, Kv10.1, h-eag
Species:
UniProtKB ID:
Gene ID:
  • Human(3756) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16510) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Rat(65198) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • cow(281881) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • chicken(421381) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic cat(101093161) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • dog(490277) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Horse(100051219) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • sheep(101120348) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Domestic Rabbit(100340515) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic guinea pig(100719620) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • naked mole-rat(101706330) potassium voltage-gated channel, subfamily H (eag-related), member 1

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Small Molecule - Antagonist

Product Number
Description
Species
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC),
Species
human
N-Desmethylclozapine, ,
Species
human
Sparfloxacin, ≥98.0% (HPLC),
Species
human
Ciprofloxacin, ≥98% (HPLC),
Species
rat, human
Ofloxacin, fluoroquinolone antibiotic,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Potassium Channel EAG-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Potassium Channel Kv10.1 (EAG-1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Nitrendipine, >95%, powder,
Species
human, rat
Pimozide, ,
Species
human, mouse, rat
Quinidine, anhydrous,
Species
mouse, human, rat
Quinidine, crystallized, ≥98.0% (dried material, NT),
Species
mouse, human, rat
Nifedipine, ≥98% (HPLC), powder,
Species
rat, mouse, human