MilliporeSigma

KCNQ1

potassium voltage-gated channel, KQT-like subfamily, member 1

Synonyms:
ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
Species:
UniProtKB ID:
Gene ID:
  • Human(3784) Summary: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(16535) potassium voltage-gated channel, subfamily Q, member 1
  • Rat(84020) potassium voltage-gated channel, KQT-like subfamily, member 1
  • chicken(423090) potassium voltage-gated channel, KQT-like subfamily, member 1
  • naked mole-rat(101725681) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic guinea pig(100379230) potassium voltage-gated channel, subfamily Q, member 1
  • sheep(101119596) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic cat(101092644) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Horse(100034129) potassium voltage-gated channel, KQT-like subfamily, member 1
  • cow(784876) potassium voltage-gated channel, KQT-like subfamily, member 1
  • dog(483669) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Zebrafish(557498) potassium voltage-gated channel, KQT-like subfamily, member 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Potassium Channel KvLQT1 Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-KCNQ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KCNQ1, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-KCNQ1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Potassium Channel Kv7.1 (KCNQ1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Retigabine, ≥98% (HPLC),
Species
human
Retigabine, analytical standard,
Species
human
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
Species
human
Guanidine hydrochloride, ,
Species
human
Guanidine hydrochloride, ≥98%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human KCNQ1,
Species
human
MISSION® esiRNA, targeting mouse Kcnq1,
Species
mouse