MilliporeSigma

SLC1A1

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

Synonyms:
EAAC1, EAAT3, SCZD18
Species:
UniProtKB ID:
Gene ID:
  • Human(6505) Summary: This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
  • Mouse(20510) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • Rat(25550) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • naked mole-rat(101713753) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • domestic guinea pig(100721255) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • Zebrafish(436939) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • chicken(427352) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • dog(403751) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • domestic cat(101099844) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • cow(282353) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
  • Domestic Rabbit(100009070) solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
Dihydrokainic acid, ≥98% (HPLC), powder,
Species
rat, human
(±)-AMPA, solid,
Species
rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC1A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-Eaac1 - Fitc antibody produced in mouse, clone S180-41, purified immunoglobulin,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Monoclonal Anti-Eaac1 - Atto 390 antibody produced in mouse, clone S180-41, purified immunoglobulin,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Monoclonal Anti-Eaac1 - Atto 488 antibody produced in mouse, clone S180-41, purified immunoglobulin,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
Monoclonal Anti-Eaac1 - Percp antibody produced in mouse, clone S180-41, purified immunoglobulin,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC1A1,
Species
human