MilliporeSigma

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Synonyms:
EAAT2, GLT-1
Species:
UniProtKB ID:
Gene ID:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
Dihydrokainic acid, ≥98% (HPLC), powder,
Species
rat, human
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Species
rat
(±)-AMPA, solid,
Species
rat
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SLC1A2 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-EAAT2/SLC1A2 Antibody, clone 7K5F7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
rat
Application

Small Molecule - Inhibitor

Product Number
Description
Species
Dihydrokainic acid, ≥98% (HPLC), powder,
Species
rat, human
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC1A2,
Species
human