MilliporeSigma

TGFB1

transforming growth factor, beta 1

Synonyms:
CED, DPD1, LAP, TGFB, TGFbeta
Species:
UniProtKB ID:
Gene ID:
  • Human(7040) Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
  • Mouse(21803) transforming growth factor, beta 1
  • Rat(59086) transforming growth factor, beta 1
  • sheep(443417) transforming growth factor, beta 1
  • domestic cat(768263) transforming growth factor, beta 1
  • naked mole-rat(101704230) transforming growth factor, beta 1
  • dog(403998) transforming growth factor, beta 1
  • Domestic Rabbit(100008645) transforming growth factor, beta 1
  • chicken(100873157) transforming growth factor beta 1
  • cow(282089) transforming growth factor, beta 1
  • Horse(100033900) transforming growth factor, beta 1
  • domestic guinea pig(100135628) transforming growth factor, beta 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human TGF-β 1 ELISA Kit, for serum, plasma, and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TGFB1, IgG fraction of antiserum,
Species Reactivity
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
western blot
Anti-TGFB1, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti- TGFB1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-TGFB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-TGFB1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot

Proteins

Product Number
Description
Species
Transforming Growth Factor-β1, human (hTGF-β1), recombinant (CHO cells),
Species
human
Transforming Growth Factor-β1 Latency Associated Peptide human, ≥97% (SDS-PAGE), recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human
Transforming Growth Factor-β1 human, TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture,
Species
human
Transforming Growth Factor-β1 human, TGF-β1, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tgfb1,
Species
mouse
MISSION® esiRNA, targeting human TGFB1,
Species
human