MilliporeSigma

TUBA3C

tubulin, alpha 3c

Synonyms:
TUBA2, bA408E5.3
Species:
UniProtKB ID:
Gene ID:
  • Human(7278) Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]
  • dog(610636) tubulin, alpha 3c

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-TUBA1/3/4 (pTyr272) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Docetaxel, purum, ≥97.0% (HPLC),
Species
human
Colchicine for system suitability A, European Pharmacopoeia (EP) Reference Standard,
Species
human
Taxol, phyproof® Reference Substance,
Species
human
Vinblastine sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Vinblastine sulfate, European Pharmacopoeia (EP) Reference Standard,
Species
human