MilliporeSigma

ZYX

zyxin

Synonyms:
ESP-2, HED-2
Species:
UniProtKB ID:
Gene ID:
  • Human(7791) Summary: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(22793) zyxin
  • Rat(114636) zyxin
  • Zebrafish(564246) zyxin
  • fruit fly(317824) Zyxin
  • domestic guinea pig(100727523) zyxin
  • naked mole-rat(101710025) zyxin
  • sheep(101123626) zyxin
  • chicken(418300) zyxin
  • dog(482736) zyxin
  • cow(768226) zyxin
  • domestic cat(101099953) zyxin

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ZYX antibody produced in mouse, clone 2D1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-ZYX antibody produced in mouse, clone 2C10-4A7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-ZYX antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
western blot
Anti-Zyxin, serum, from rabbit,
Species Reactivity
human, monkey, mouse
Application
immunocytochemistry
western blot
Anti-Zyxin Antibody, clone 14E11.1, clone 14E11.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot

Proteins

Product Number
Description
Species
Monoclonal Anti-ZYX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2502, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human
PrEST Antigen ZYX, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen ZYX, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Zyx,
Species
mouse