MilliporeSigma

ACTA1

actin, alpha 1, skeletal muscle

Synonyms:
ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
Species:
UniProtKB ID:
Gene ID:
  • Human(58) Summary: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
  • Mouse(11459) actin, alpha 1, skeletal muscle
  • Rat(29437) actin, alpha 1, skeletal muscle
  • naked mole-rat(101721383) actin, alpha 1, skeletal muscle
  • cow(281592) actin, alpha 1, skeletal muscle
  • sheep(101107662) actin, alpha 1, skeletal muscle
  • chicken(421534) actin, alpha 1, skeletal muscle
  • Horse(100065454) actin, alpha 1, skeletal muscle
  • dog(488984) actin, alpha 1, skeletal muscle
  • domestic cat(101095439) actin, alpha 1, skeletal muscle
  • domestic guinea pig(100716933) actin, alpha 1, skeletal muscle

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-alpha-Actin Antibody, Smooth Muscle, from rabbit, purified by affinity chromatography,
Species Reactivity
chicken, human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Actin Antibody, Alexa Fluor 488 Conjugate, from rabbit, ALEXA FLUOR 488,
Species Reactivity
human, mouse
Application
flow cytometry
immunocytochemistry

immunofluorescence
Anti-Actin Antibody, clone C4, Alexa Fluor 488 conjugated, clone C4, Chemicon®, from mouse,
Species Reactivity
chicken, human
Application
immunofluorescence
Anti-Actin, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Actin Antibody, Alexa Fluor 647 Conjugate, from rabbit, ALEXA FLUOR 647,
Species Reactivity
human, mouse
Application
flow cytometry
immunocytochemistry

immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACTA1,
Species
human