MilliporeSigma

ADRB2

adrenoceptor beta 2, surface

Synonyms:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species:
UniProtKB ID:
Gene ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Product Number
Description
Species
Albuterol sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Salbutamol hemisulfate salt, ≥98%,
Species
human
Metaproterenol hemisulfate salt, ,
Species
human
Salbutamol sulfate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Clenbuterol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Species
human
Timolol maleate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Timolol maleate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Esmolol hydrochloride, ≥98% (HPLC), solid,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADRB2, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-phospho-Adrenergic Receptor β2 (pSer346) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Species
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Species
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADRB2,
Species
human
MISSION® esiRNA, targeting mouse Adrb2,
Species
mouse