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CASP6

caspase 6, apoptosis-related cysteine peptidase

Synonyms:
MCH2
Species:
UniProtKB ID:
Gene ID:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Caspase-6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry

western blot
Anti-Caspase-6 Antibody, clone 2W4G2, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot
Anti-Caspase-6 Antibody, clone 6D7S2, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Species
human
Caspase Inhibitor, ,
Species
human
NSCI, ≥97% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CASP6,
Species
human
MISSION® esiRNA, targeting mouse Casp6,
Species
mouse