MilliporeSigma

CDH5

cadherin 5, type 2 (vascular endothelium)

Synonyms:
7B4, CD144
Species:
UniProtKB ID:
Gene ID:
  • Human(1003) Summary: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(12562) cadherin 5
  • Rat(307618) cadherin 5
  • naked mole-rat(101706580) cadherin 5, type 2 (vascular endothelium)
  • domestic guinea pig(100727685) cadherin 5, type 2 (vascular endothelium)
  • sheep(101107462) cadherin 5, type 2 (vascular endothelium)
  • Domestic Rabbit(100301529) cadherin 5, type 2 (vascular endothelium)
  • chicken(374068) cadherin 5, type 2 (vascular endothelium)
  • domestic cat(101084501) cadherin 5, type 2 (vascular endothelium)
  • cow(414735) cadherin 5, type 2 (vascular endothelium)
  • dog(489775) cadherin 5, type 2 (vascular endothelium)
  • Zebrafish(445471) cadherin 5

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VE-Cadherin (CD144) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-phospho-VE-Cadherin (pTyr731) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-VE-Cadherin (Tyr685) Antibody, Alexa Fluor 555 Conjugate, from rabbit, ALEXA FLUOR 555,
Species Reactivity
bovine, human, porcine
Application
immunocytochemistry
Anti-VE-cadherin Antibody, clone BV6, clone BV6, from mouse,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-VE-cadherin (Tyr731), from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
inhibition assay
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CDH5,
Species
human
MISSION® esiRNA, targeting mouse Cdh5,
Species
mouse