MilliporeSigma

CHAT

choline O-acetyltransferase

Synonyms:
CHOACTASE, CMS1A, CMS1A2
Species:
UniProtKB ID:
Gene ID:
  • Human(1103) Summary: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
  • Mouse(12647) choline acetyltransferase
  • Rat(290567) choline O-acetyltransferase
  • sheep(101117817) choline O-acetyltransferase
  • domestic guinea pig(100718930) choline O-acetyltransferase
  • naked mole-rat(101711939) choline O-acetyltransferase
  • Thale Cress(821249) acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase
  • cow(524732) choline O-acetyltransferase
  • domestic cat(751512) choline O-acetyltransferase
  • Zebrafish(100170938) choline acetyltransferase
  • chicken(395314) choline O-acetyltransferase
  • dog(486775) choline O-acetyltransferase

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
Anti-CHAT, affinity isolated antibody,
Species Reactivity
dog, horse, human
Application
western blot
Anti-CHAT antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-CHAT antibody produced in mouse, clone 1H7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-Choline acetyltransferase antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, chimpanzee, human, pig
Application
ELISA
western blot

Small Molecule - Cofactor

Product Number
Description
Species
Acetyl coenzyme A lithium salt, ≥93% (HPLC),
Species
human, mouse, rat
Acetyl coenzyme A trisodium salt, ≥93% (HPLC), powder,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHAT,
Species
human
MISSION® esiRNA, targeting mouse Chat,
Species
mouse