MilliporeSigma

CHD3

chromodomain helicase DNA binding protein 3

Synonyms:
Mi-2a, Mi2-ALPHA, ZFH
Species:
UniProtKB ID:
Gene ID:
  • Human(1107) Summary: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(216848) chromodomain helicase DNA binding protein 3
  • Rat(303241) chromodomain helicase DNA binding protein 3
  • naked mole-rat(101704396) chromodomain helicase DNA binding protein 3
  • domestic guinea pig(100732819) chromodomain helicase DNA binding protein 3
  • fruit fly(40111) CG9594 gene product from transcript CG9594-RA
  • Zebrafish(568230) chromodomain helicase DNA binding protein 3
  • domestic cat(101100517) chromodomain helicase DNA binding protein 3
  • Domestic Rabbit(100342829) chromodomain helicase DNA binding protein 3
  • dog(479489) chromodomain helicase DNA binding protein 3
  • cow(532673) chromodomain helicase DNA binding protein 3
  • sheep(101119918) chromodomain helicase DNA binding protein 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHD3 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-CHD-3 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot
Anti-CHD3 Antibody, clone 2G4, ascites fluid, clone 2G4, from mouse,
Species Reactivity
human, mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-CHD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CHD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHD3,
Species
human