MilliporeSigma

CLDN6

claudin 6

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(9074) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010]
  • Mouse(54419) claudin 6
  • Rat(287098) claudin 6
  • naked mole-rat(101723329) claudin 6
  • domestic guinea pig(100735319) claudin 6
  • cow(511318) claudin 6
  • sheep(101117294) claudin 6
  • dog(490048) claudin 6
  • domestic cat(101100433) claudin 6

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Claudin 6 (pTyr219) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-Claudin-6 Antibody, clone 2, ,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

inhibition assay

western blot
Anti-Claudin 6 Antibody, clone 1B22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-CLDN6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rabbit
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cldn6,
Species
mouse
MISSION® esiRNA, targeting human CLDN6,
Species
human