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COL1A1

collagen, type I, alpha 1

Synonyms:
OI4
Species:
UniProtKB ID:
Gene ID:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-COL1A1 antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Collagen Type I Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®,
Species Reactivity
human
Application
immunohistochemistry
Milli-Mark® Anti-Collagen Type I-FITC Antibody, clone 5D8-G9, clone 5D8-G9, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
Anti-Rat Collagen Type I Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
immunocytochemistry

immunohistochemistry

radioimmunoassay

Proteins

Product Number
Description
Species
Collagen from calf skin, Bornstein and Traub Type I, solid, BioReagent, suitable for cell culture,
Species
cow
Human Collagen Type I, ,
Species
human
Collagen Type I, rat tail, ,
Species
rat
Collagen solution from bovine skin, Type I, 2.9-3.2 mg/mL, suitable for cell culture, sterile-filtered,
Species
cow
Millicoat® Human Collagen Type I Coated Strips (96-Wells), 96-well plate coated with human Collagen Type I used for cell adhesion studies.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COL1A1,
Species
human
MISSION® esiRNA, targeting mouse Col1a1,
Species
mouse