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COL1A1

collagen, type I, alpha 1

Synonyms:
OI4
Species:
UniProtKB ID:
Gene ID:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Collagen Type I/III, Cyanogen Bromide Fragments Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human, mouse, rat
Application
Anti-Collagen Types I, II & III Antibody, clone MMCHABC, clone MMCHABC, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

radioimmunoassay
Anti-Mouse Collagen Type I Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse
Application
ELISA
immunohistochemistry

radioimmunoassay

western blot
Anti-Collagen Type I Antibody, biotin conjugated, Chemicon®, from goat,
Species Reactivity
bovine, human
Application
ELISA
dot blot

immunohistochemistry

western blot
Anti-Collagen Type I Antibody, Chemicon®, from goat,
Species Reactivity
bovine, human
Application
ELISA
dot blot

immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
SILuLite COL1A1 N-terminal propeptide human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human
SILuProt COL1A1 N-terminal propeptide human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human
Collagen, Type I solution from rat tail, BioReagent, suitable for cell culture, sterile-filtered,
Species
rat
Collagen from rat tail, Bornstein and Traub Type I, powder, BioReagent, suitable for cell culture,
Species
rat
Collagen Type I, rat tail, ,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Col1a1,
Species
mouse
MISSION® esiRNA, targeting human COL1A1,
Species
human