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COL1A1

collagen, type I, alpha 1

Synonyms:
OI4
Species:
UniProtKB ID:
Gene ID:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Collagen Type I antibody, Mouse monoclonal, clone COL-1, purified from hybridoma cell culture,
Species Reactivity
bovine, deer, human, pig, rat
Application
ELISA
dot blot

immunohistochemistry

western blot
Anti-Telo-Collagen Type I, A1/COL1A1, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, sheep
Application
flow cytometry
immunohistochemistry

western blot
Anti-COL1A1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-COL1A1 antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Collagen Type I Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Millicoat® Human Collagen Type I Coated Strips (96-Wells), 96-well plate coated with human Collagen Type I used for cell adhesion studies.,
Species
human
Collagen, from rat tail tendon,
Species
rat
Rat Tail Collagen Coating Solution (20 ML), Type I, 50 μg/mL, solution, BioReagent, suitable for cell culture,
Species
rat
Collagen from calf skin, Bornstein and Traub Type I, solid, BioReagent, suitable for cell culture,
Species
cow
Human Collagen Type I, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COL1A1,
Species
human
MISSION® esiRNA, targeting mouse Col1a1,
Species
mouse