MilliporeSigma

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

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Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Isoguvacine hydrochloride, solid,
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Species
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
Zolpidem, ≥98% (HPLC), solid,
Species
human, rat
trans-Dehydroandrosterone, ≥99%,
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Ro 15-4513, solid,
Species
rat, human
Picrotoxin, powder,
Species
human
Pregnenolone sulfate sodium salt, ,
Species
human
SR-95531, ≥98% (HPLC), powder,
Species
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABA A Receptor α 5 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Atto 488 antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
L-655,708, ≥98% (HPLC), powder,
Species
human
Etomidate, >98% (HPLC), powder,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
Carbamazepine, powder,
Species
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRA5,
Species
human