MilliporeSigma

GZMH

granzyme H (cathepsin G-like 2, protein h-CCPX)

Synonyms:
CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2
Species:
UniProtKB ID:
Gene ID:
  • Human(2999) Summary: The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
  • cow(617313) granzyme H (cathepsin G-like 2, protein h-CCPX)
  • dog(490629) granzyme H (cathepsin G-like 2, protein h-CCPX)
  • naked mole-rat(101702503) granzyme H (cathepsin G-like 2, protein h-CCPX)
  • domestic cat(100113476) granzyme H (cathepsin G-like 2, protein h-CCPX)
  • cow(788601) granzyme H (cathepsin G-like 2, protein h-CCPX)
  • domestic guinea pig(100720497) granzyme H (cathepsin G-like 2, protein h-CCPX)

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ELISA

Product Number
Description
Species
Human Granzyme H ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GZMH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GZMH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GZMH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GRAH antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GZMH,
Species
human