MilliporeSigma

IL7

interleukin 7

Synonyms:
IL-7
Species:
UniProtKB ID:
Gene ID:
  • Human(3574) Summary: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
  • Mouse(16196) interleukin 7
  • Rat(25647) interleukin 7
  • chicken(420193) interleukin 7
  • dog(751768) interleukin 7
  • domestic cat(101084597) interleukin 7
  • cow(280827) interleukin 7
  • sheep(443341) interleukin 7
  • domestic guinea pig(100725811) interleukin 7
  • naked mole-rat(101713773) interleukin 7

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Mouse IL-7 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Human IL-7 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL7 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-IL7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1, clone 7B1.1, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot

Proteins

Product Number
Description
Species
Interleukin-7 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-7 human, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
IL-7 from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
rat
IL-7 human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL7,
Species
human