MilliporeSigma

IL7R

interleukin 7 receptor

Synonyms:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Species:
UniProtKB ID:
Gene ID:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor

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ELISA

Product Number
Description
Species
Human IL-7 R alpha ELISA, for serum, plasma and cell culture supernatants,
Species
human
Mouse Il7r / Interleukin-7 Receptor Subunit Alpha ELISA Kit, ,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-IL7R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CD127 (IL-7Ra) (mouse), violetFluor® 450, clone A7R34 Antibody, clone A7R34, from rat, violetFluor® 450,
Species Reactivity
mouse
Application
flow cytometry
Anti-IL7R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-CD127/IL7R antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL7R,
Species
human