MilliporeSigma

KPNA6

karyopherin alpha 6 (importin alpha 7)

Synonyms:
IPOA7, KPNA7
Species:
UniProtKB ID:
Gene ID:
  • Human(23633) Summary: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008]
  • Mouse(16650) karyopherin (importin) alpha 6
  • Rat(362607) karyopherin alpha 6 (importin alpha 7)
  • cow(531602) karyopherin alpha 6 (importin alpha 7)
  • dog(487314) karyopherin alpha 6 (importin alpha 7)
  • chicken(419656) karyopherin alpha 6 (importin alpha 7)
  • domestic guinea pig(100724106) karyopherin alpha 6 (importin alpha 7)
  • sheep(101117141) karyopherin alpha 6 (importin alpha 7)
  • naked mole-rat(101709271) karyopherin alpha 6 (importin alpha 7)
  • domestic cat(101097823) karyopherin alpha 6 (importin alpha 7)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KPNA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-KPNA6 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kpna6,
Species
mouse
MISSION® esiRNA, targeting human KPNA6,
Species
human