MilliporeSigma

NPM1

nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Synonyms:
B23, NPM
Species:
UniProtKB ID:
Gene ID:
  • Human(4869) Summary: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
  • Mouse(18148) nucleophosmin 1
  • Rat(25498) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • chicken(396203) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • naked mole-rat(101701761) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • domestic guinea pig(101788218) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • domestic cat(101094904) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • sheep(101104783) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • Domestic Rabbit(100328693) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • cow(614028) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • dog(479292) nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-NPM1-T199 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-NPM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Nucleophosmin antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP236, affinity isolated antibody,
Species Reactivity
bovine, chicken, human, mouse, rat
Application
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-NPM1 antibody produced in mouse, clone 1B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-NPM1 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Npm1,
Species
mouse
MISSION® esiRNA, targeting human NPM1,
Species
human