MilliporeSigma

PPARG

peroxisome proliferator-activated receptor gamma

Synonyms:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Species:
UniProtKB ID:
Gene ID:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

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Small Molecule - Activator

Product Number
Description
Species
Ciglitizone, ≥98% (HPLC),
Species
mouse, human
2-(p-Chlorophenoxy)-2-methylpropionic acid, 97%,
Species
mouse, human
WY-14643, ,
Species
rat, human, mouse
Bezafibrate, ≥98%, solid,
Species
mouse, human

Small Molecule - Agonist

Product Number
Description
Species
Pioglitazone for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Rosiglitazone, ≥98% (HPLC),
Species
human
Pioglitazone, ,
Species
human
Pioglitazone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Pioglitazone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
GW9662, >98% (HPLC),
Species
human
Troglitazone, ≥98% (HPLC),
Species
human
Ciglitizone, ≥98% (HPLC),
Species
mouse, human
GW0742, ≥98% (HPLC),
Species
human
CDDO Methyl Ester, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PPARG (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-PPAR-γ antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-PPARG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PPARG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-phospho-PPARgamma (Ser112) Antibody, clone AW504 rabbit monoclonal, ,
Species Reactivity
Application
western blot

Proteins

Product Number
Description
Species
PPAR γ, ligand binding domain (204-477), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
PPAR, γ human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pparg,
Species
mouse
MISSION® esiRNA, targeting human PPARG,
Species
human