MilliporeSigma

PTPRN2

protein tyrosine phosphatase, receptor type, N polypeptide 2

Synonyms:
IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
Species:
UniProtKB ID:
Gene ID:
  • Human(5799) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19276) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Rat(29714) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Zebrafish(325033) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • domestic cat(101089683) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • naked mole-rat(101716326) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • domestic guinea pig(100723726) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Horse(100067294) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • chicken(420449) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • dog(482825) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Domestic Rabbit(100340246) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • cow(616515) protein tyrosine phosphatase, receptor type, N polypeptide 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PTPRN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PTPRN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PTPRN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PTPRN2 antibody produced in mouse, clone 7F8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTPRN2,
Species
human
MISSION® esiRNA, targeting mouse Ptprn2,
Species
mouse