MilliporeSigma

PVRL4

poliovirus receptor-related 4

Synonyms:
EDSS1, LNIR, PRR4, nectin-4
Species:
UniProtKB ID:
Gene ID:
  • Human(81607) Summary: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
  • Mouse(71740) poliovirus receptor-related 4
  • Rat(498281) poliovirus receptor-related 4
  • dog(609931) poliovirus receptor-related 4
  • domestic guinea pig(100734333) poliovirus receptor-related 4
  • Horse(100066309) poliovirus receptor-related 4
  • cow(507718) poliovirus receptor-related 4
  • Zebrafish(794920) poliovirus receptor-related 4
  • naked mole-rat(101710379) poliovirus receptor-related 4
  • domestic cat(101092485) poliovirus receptor-related 4
  • Domestic Rabbit(100348580) poliovirus receptor-related 4
  • sheep(101123428) poliovirus receptor-related 4

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ELISA

Product Number
Description
Species
Human Nectin-4 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PVRL4 antibody, Mouse monoclonal, clone N4.101.10, purified from hybridoma cell culture,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
Anti-Nectin-4/PVRL4 Antibody, clone N4.61, clone N4.61.2, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)
Anti-NECTIN4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-PVRL4 antibody produced in mouse, clone 1D7, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-PVRL4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot