MilliporeSigma

QPRT

quinolinate phosphoribosyltransferase

Synonyms:
QPRTase
Species:
UniProtKB ID:
Gene ID:
  • Human(23475) Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008]
  • Mouse(67375) quinolinate phosphoribosyltransferase
  • Rat(293504) quinolinate phosphoribosyltransferase
  • cow(614254) quinolinate phosphoribosyltransferase
  • domestic guinea pig(100727900) quinolinate phosphoribosyltransferase
  • sheep(101102696) quinolinate phosphoribosyltransferase
  • domestic cat(101087441) quinolinate phosphoribosyltransferase
  • dog(607664) quinolinate phosphoribosyltransferase
  • naked mole-rat(101718250) quinolinate phosphoribosyltransferase
  • Goat(100861315) quinolinate phosphoribosyltransferase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-QPRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-QPRT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-QPRT antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human QPRT,
Species
human