MilliporeSigma

SPTAN1

spectrin, alpha, non-erythrocytic 1

Synonyms:
EIEE5, NEAS, SPTA2
Species:
UniProtKB ID:
Gene ID:
  • Human(6709) Summary: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
  • Mouse(20740) spectrin alpha, non-erythrocytic 1
  • Rat(64159) spectrin, alpha, non-erythrocytic 1
  • dog(403484) spectrin, alpha, non-erythrocytic 1
  • domestic cat(101080748) spectrin, alpha, non-erythrocytic 1
  • chicken(374234) spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
  • Horse(100066945) spectrin, alpha, non-erythrocytic 1
  • sheep(101107431) spectrin, alpha, non-erythrocytic 1
  • domestic guinea pig(100715698) spectrin, alpha, non-erythrocytic 1
  • Domestic Rabbit(100350866) spectrin, alpha, non-erythrocytic 1
  • cow(540108) spectrin, alpha, non-erythrocytic 1
  • naked mole-rat(101701130) spectrin, alpha, non-erythrocytic 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Alpha Fodrin Antibody, clone 9H5V8, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-SNTF (cleaved spectrin), serum, from rabbit,
Species Reactivity
bovine, human, mouse, porcine, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Fodrin Mouse mAb (Fod009), liquid, clone Fod009, Calbiochem®,
Species Reactivity
bovine, canine, human, mouse, porcine, rabbit, rat
Application
Anti-Spectrin α Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-SPTAN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPTAN1,
Species
human