Skip to Content
MilliporeSigma

SRD5A3

steroid 5 alpha-reductase 3

Synonyms:
CDG1P, CDG1Q, KRIZI, SRD5A2L, SRD5A2L1
Species:
UniProtKB ID:
Gene ID:
  • Human(79644) Summary: The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
  • Mouse(57357) steroid 5 alpha-reductase 3
  • Rat(305291) steroid 5 alpha-reductase 3
  • chicken(422750) steroid 5 alpha-reductase 3
  • cow(535834) steroid 5 alpha-reductase 3
  • sheep(101106772) steroid 5 alpha-reductase 3
  • dog(482155) steroid 5 alpha-reductase 3
  • domestic cat(101090010) steroid 5 alpha-reductase 3
  • domestic guinea pig(100727041) steroid 5 alpha-reductase 3
  • naked mole-rat(101726767) steroid 5 alpha-reductase 3
  • Zebrafish(560717) steroid 5 alpha-reductase 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Inhibitor

Product Number
Description
Species
Dutasteride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Dutasteride, ≥98% (HPLC),
Species
human
Dutasteride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Dutasteride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SRD5A3,
Species
human
MISSION® esiRNA, targeting mouse Srd5a3,
Species
mouse