SVIL
supervillin
Synonyms:
Species:
Human SVIL (6840), Mouse Svil (225115), Rat Svil (361256), cow SVIL (281509), dog SVIL (477965), domestic cat SVIL (101098723), domestic guinea pig Svil (100729448), Horse SVIL (100063045), naked mole-rat Svil (101713658), chicken SVIL (420475)
UniProtKB ID:
Gene ID:
- Human(6840) Summary: This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
- Mouse(225115) supervillin
- Rat(361256) supervillin
- cow(281509) supervillin
- dog(477965) supervillin
- domestic cat(101098723) supervillin
- domestic guinea pig(100729448) supervillin
- Horse(100063045) supervillin
- naked mole-rat(101713658) supervillin
- chicken(420475) supervillin
- sheep(101119493) supervillin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human
Application
immunohistochemistry
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-SVIL antibody produced in mouse, clone 6E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Supervillin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
western blot