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TCEB1

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

Synonyms:
SIII, eloC
Species:
UniProtKB ID:
Gene ID:
  • Human(6921) Summary: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
  • Mouse(67923) transcription elongation factor B (SIII), polypeptide 1
  • Rat(64525) transcription elongation factor B (SIII), polypeptide 1
  • domestic guinea pig(100729701) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • cow(540859) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • chicken(420187) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • sheep(101107798) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • domestic cat(100628309) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • dog(477914) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
  • naked mole-rat(101723674) transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ELOC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TCEB1,
Species
human
MISSION® esiRNA, targeting mouse Tceb1,
Species
mouse