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TMPRSS2

transmembrane protease, serine 2

Synonyms:
PP9284, PRSS10
Species:
UniProtKB ID:
Gene ID:
  • Human(7113) Summary: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(50528) transmembrane protease, serine 2
  • Rat(156435) transmembrane protease, serine 2
  • cow(511037) transmembrane protease, serine 2
  • sheep(101120216) transmembrane protease, serine 2
  • Zebrafish(494080) transmembrane protease, serine 2
  • chicken(418528) transmembrane protease, serine 2
  • domestic cat(101096004) transmembrane protease, serine 2
  • naked mole-rat(101715175) transmembrane protease, serine 2
  • domestic guinea pig(100732077) transmembrane protease, serine 2
  • dog(487770) transmembrane protease, serine 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TMPRSS2, (C-terminal) antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-TMPRSS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-TMPRSS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TMPRSS2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-TMPRSS2 Antibody, clone P5H9-A3, clone P5H9-A3, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TMPRSS2,
Species
human