105171

5-Methoxy-2-methyl-3-indoleacetic acid

98%

• Synonym(s): N-Des(4-chlorobenzoyl)indomethacin, NSC 97026, 2-(5-Methoxy-2-methyl-1H-indol-3-yl)acetic acid
• Empirical Formula (Hill Notation): C₁₂H₁₃NO₃
• CAS Number: 2882-15-7
• Molecular Weight: 219.24
• NACRES: NA.22
• PubChem Substance ID: 24846692
• UNSPSC Code: 12352100
• EC Number: 220-734-7
• MDL number: MFCD00005618
• Assay: 98%

Properties

• Quality Segment: 100
• assay: 98%
• mp: 161-163 °C (lit.)
• solubility: methanol: soluble
• functional group: carboxylic acid
• SMILES string: COc1ccc2[nH]c(C)c(CC(O)=O)c2c1
• InChI: 1S/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15)
• InChI key: TXWGINUZLBAKDF-UHFFFAOYSA-N

Description

General description

5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

Application

5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)