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243213

Sigma-Aldrich

Carnauba wax No. 1 yellow

refined

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Synonym(s):
Brazil wax
CAS Number:
8015-86-9
EC Number:
232-399-4
MDL number:
MFCD00130724
NACRES:
NA.23

Quality Level

200

form

powder

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This Item
4116631096860432288
Sigma-Aldrich

Sigma-Aldrich

243213

Carnauba wax No. 1 yellow

Paraffin wax mp ≥65 °C (ASTM D 87)

Sigma-Aldrich

411663

Paraffin wax

USP

USP

1096860

Carnauba Wax

Candelilla wax

Sigma-Aldrich

432288

Candelilla wax

General description

Carnauba wax No.1 yellow(CW) is an ester based wax that can be extracted from palm leaves. The composition of this wax contains aliphatic esters, ω-hydroxy esters and unsaturated alcohols. It can be used as a glossing agent in a variety of pharmaceutical products.

Application

CW may be used as a hydrophobic excipient which can be used to modify the kinetics of polymeric gel in a drug releasing system. It can be used in dry polymeric coatings which can increase the crystallization and improve the stability of amorphous solid drug formulations. It may also be used as a component of lipids which can be used to tune and improve the flowability and designing of solid drugs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1. Microcalorimetric investigation.
Em?s M and Nyqvist H
International Journal of Pharmaceutics, 197(1-2), 117-127 (2000)
Carnauba wax as a promising excipient in melt granulation targeting the preparation of mini-tablets for sustained release of highly soluble drugs.
Nart V, et al.
Materials Science and Engineering, C, 70(6), 250-257 (2017)
Enhanced physical stability of amorphous drug formulations via dry polymer coating.
Capece M and Dave R
Journal of Pharmaceutical Sciences, 104(6), 2076-2084 (2015)
Effect of hydrophobic inclusions on polymer swelling kinetics studied by magnetic resonance imaging.
Gajdosova M, et al
International Journal of Pharmaceutics, 500(1-2), 136-143 (2016)
S Nikolić et al.
International journal of pharmaceutics, 414(1-2), 276-284 (2011-05-24)
A photoprotective formulation was developed with an increased sunprotection factor (SPF), compared to a conventional nanoemulsion, but having the same concentration of three molecular sunscreens, namely ethylhexyl triazone, bis-ethylhexyloxyphenol methoxyphenyl triazine, and ethylhexyl methoxycinnamate. The sunscreen mixture was incorporated into
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