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Sigma-Aldrich

2,6-Diaminopurine

98%

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About This Item

Empirical Formula (Hill Notation):
C5H6N6
CAS Number:
Molecular Weight:
150.14
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

98%

mp

>300 °C (lit.)

SMILES string

Nc1nc(N)c2nc[nH]c2n1

InChI

1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11)

InChI key

MSSXOMSJDRHRMC-UHFFFAOYSA-N

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Makoto Komiyama et al.
Nature protocols, 3(4), 646-654 (2008-04-05)
Pseudo-complementary peptide nucleic acid (pcPNA) is a DNA analog in which modified DNA bases 2,6-diaminopurine (D) and 2-thiouracil (U(s)) 'decorate' a poly[N-(2-aminoethyl)glycine] backbone, together with guanine (G) and cytosine (C). One of the most significant characteristics of pcPNA is its
Anna K Shchyolkina et al.
Nucleic acids research, 34(11), 3239-3245 (2006-06-27)
Several cellular processes involve alignment of three nucleic acids strands, in which the third strand (DNA or RNA) is identical and in a parallel orientation to one of the DNA duplex strands. Earlier, using 2-aminopurine as a fluorescent reporter base
Alexander Fuhrmann et al.
Biophysical journal, 102(10), 2381-2390 (2012-06-09)
Electron-tunneling data suggest that a noncovalently-bonded complex of three molecules, two recognition molecules that present hydrogen-bond donor and acceptor sites via a carboxamide group, and a DNA base, remains bound for seconds. This is surprising, given that imino-proton exchange rates
Rodolphe Suspène et al.
Nucleic acids research, 36(12), e72-e72 (2008-06-03)
DNA complementarity is expressed by way of three hydrogen bonds for a G:C base pair and two for A:T. As a result, careful control of the denaturation temperature of PCR allows selective amplification of AT-rich alleles. Yet for the same
Asif Hayat et al.
Molecules (Basel, Switzerland), 24(9) (2019-05-11)
This work incorporates a variety of conjugated donor-acceptor (DA) co-monomers such as 2,6-diaminopurine (DP) into the structure of a polymeric carbon nitride (PCN) backbone using a unique nanostructure co-polymerization strategy and examines its photocatalytic activity performance in the field of

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