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Sigma-Aldrich

(S)-(−)-N-(Trifluoroacetyl)pyrrolidine-2-carbonyl chloride solution

0.1 M in methylene chloride

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Synonym(s):
(S)-(−)-N-(Trifluoroacetyl)prolyl chloride solution, TPC
Empirical Formula (Hill Notation):
C7H7ClF3NO2
CAS Number:
36724-68-2
Molecular Weight:
229.58
Beilstein/REAXYS Number:
480791
MDL number:
MFCD00010418
UNSPSC Code:
12352005
PubChem Substance ID:
24854932
NACRES:
NA.22

optical purity

ee: 97% (GLC)

Quality Level

100

concentration

0.1 M in methylene chloride

refractive index

n20/D 1.424

density

1.308 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)N1CCC[C@H]1C(Cl)=O

InChI

1S/C7H7ClF3NO2/c8-5(13)4-2-1-3-12(4)6(14)7(9,10)11/h4H,1-3H2/t4-/m0/s1

InChI key

NUOYJPPISCCYDH-BYPYZUCNSA-N

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Application

(S)-(−)-N-(Trifluoroacetyl)pyrrolidine-2-carbonyl chloride can be used as a chiral derivatization reagent:
  • In the chiral separation of psychoactive, cathinone- and amphetamine-related drugs using GC-MS technique.
  • In the estimation of cathinone related drug enantiomers in biological samples like urine and plasma using GC-MS technique.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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