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42358

Sigma-Aldrich

Dioctadecylamine

≥99.0% (NT)

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Synonym(s):
DODA, Distearylamine
Linear Formula:
[CH3(CH2)17]2NH
CAS Number:
Molecular Weight:
521.99
Beilstein:
1801688
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Assay

≥99.0% (NT)

mp

71-73 °C

solubility

water: soluble(lit.)

SMILES string

CCCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC

InChI

1S/C36H75N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37H,3-36H2,1-2H3

InChI key

HKUFIYBZNQSHQS-UHFFFAOYSA-N

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This Item
30539139423874750
Dioctadecylamine ≥99.0% (NT)

Sigma-Aldrich

42358

Dioctadecylamine

Octadecylamine ≥99% (GC)

Sigma-Aldrich

305391

Octadecylamine

Pyrrolidine ≥99.5%, purified by redistillation

Sigma-Aldrich

394238

Pyrrolidine

Octadecylamine ≥99.0% (GC)

Sigma-Aldrich

74750

Octadecylamine

mp

71-73 °C

mp

50-52 °C (lit.)

mp

-

mp

50-52 °C (lit.), 52-55 °C

solubility

water: soluble(lit.)

solubility

-

solubility

water: miscible

solubility

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

General description

Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed. It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed. The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9. DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.

Application

Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:
  • Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.
  • Lipid derivatives of bisethylnorspermine (BSP).
  • Functional VP (N-vinylpyrrolidone ) polymers.
It may be used in the following studies:
  • As a reactant in the synthesis of 4,4′-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4′-azobis(4-cyanovalerate).
  • As a reagent in the synthesis of dioctadecyl heptapeptides.
  • As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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