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435716

Sigma-Aldrich

3-(Trihydroxysilyl)propyl methylphosphonate, monosodium salt solution

50 wt. % in H2O

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Synonym(s):
Sodium 3-trihydroxysilylpropyl methylphosphonate
Linear Formula:
CH3P(O)(ONa)O(CH2)3Si(OH)3
CAS Number:
84962-98-1
Molecular Weight:
238.18
EC Number:
284-799-3
MDL number:
MFCD00274617
UNSPSC Code:
12352100
PubChem Substance ID:
24867253
NACRES:
NA.22

form

liquid

Quality Level

100

concentration

50 wt. % in H2O

impurities

4 wt. % methyl alcohol
4 wt. % other silane-based salts
5 wt. % sodium methyl methylphosphonate

density

1.252 g/mL at 25 °C

SMILES string

[Na+].CP([O-])(=O)OCCC[Si](O)(O)O

InChI

1S/C4H13O6PSi.Na/c1-11(5,6)10-3-2-4-12(7,8)9;/h7-9H,2-4H2,1H3,(H,5,6);/q;+1/p-1

InChI key

MKAWPVONNWUREJ-UHFFFAOYSA-M

Related Categories

Application

3-(Trihydroxysilyl)propyl methylphosphonate, monosodium salt was used for the following syntheses:
  • near-infrared dye-doped nanoparticles (NPs)
  • as single silica source for the fabrication of phosphonate-rich organosilica layered hybrid material (PSLM)
  • Gd/SiO2 nanoparticles
  • mesoporous silica nanoparticles
  • CdSe/ZnS/silica functionalized nanocrystals

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H371

Hazard Classifications

STOT SE 2

target_organs

Eyes,Central nervous system

wgk_germany

WGK 3

flash_point_f

174.2 °F

flash_point_c

79 °C

Certificates of Analysis (COA)

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Robert I Nooney et al.
Analytical and bioanalytical chemistry, 393(4), 1143-1149 (2008-10-11)
There is substantial interest in the development of near-infrared dye-doped nanoparticles (NPs) for a range of applications including immunocytochemistry, immunosorbent assays, flow cytometry, and DNA/protein microarray analysis. The main motivation for this work is the significant increase in NP fluorescence
Preparation and properties of various magnetic nanoparticles.
Drbohlavova J, et al.
Sensors, 9(4), 2352-2362 (2009)
Chris Daikopoulos et al.
Journal of hazardous materials, 270, 118-126 (2014-02-26)
A phosphonate-rich organosilica layered hybrid material (PSLM) made of 3-(trihydroxysilyl)propyl methylphosphonate, monosodium salt, as the single silica source, has been obtained from its aqueous solution through a xerogel process and mild thermal aging. The method is simple, affording bulk quantities
Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells.
Christopher Hom et al.
Small (Weinheim an der Bergstrasse, Germany), 6(11), 1185-1190 (2010-05-13)
Khaled AbouAitah et al.
Cancers, 12(1) (2020-01-16)
Antimitotics are important anticancer agents and include the natural alkaloid prodrug colchicine (COL). However, a major challenge of using COL as an anticancer drug is its cytotoxicity. We developed a novel drug delivery system (DDS) for COL using mesoporous silica
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