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684090

Sigma-Aldrich

2-Aminopyridine-3-carboxamide

97%

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Synonym(s):
2-Aminonicotinamide
Empirical Formula (Hill Notation):
C6H7N3O
CAS Number:
Molecular Weight:
137.14
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

powder

mp

194-200 °C

SMILES string

NC(=O)c1cccnc1N

InChI

1S/C6H7N3O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,7,9)(H2,8,10)

InChI key

HTPCDVLWYUXWQR-UHFFFAOYSA-N

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2-Aminopyridine-3-carboxamide 97%

684090

2-Aminopyridine-3-carboxamide

2-Aminopyrimidine 97%

A78608

2-Aminopyrimidine

2-Aminopyridine 99%

A77997

2-Aminopyridine

form

powder

form

solid

form

powder

form

crystals

mp

194-200 °C

mp

82-86 °C

mp

122-126 °C (lit.)

mp

54-58 °C (lit.)

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Christopher L Frank et al.
Toxicological sciences : an official journal of the Society of Toxicology, 160(1), 121-135 (2017-10-04)
Less than 1% of environmental chemicals have been evaluated for developmental neurotoxicity (DNT). Current guideline DNT studies are resource intensive and not amenable to screening large numbers of compounds for hazard. As part of evaluating a battery of more rapid
Haizhen Wang et al.
Nature, 546(7658), 426-430 (2017-06-14)
D-type cyclins (D1, D2 and D3) and their associated cyclin-dependent kinases (CDK4 and CDK6) are components of the core cell cycle machinery that drives cell proliferation. Inhibitors of CDK4 and CDK6 are currently being tested in clinical trials for patients
Joshua A Harrill et al.
Toxicology and applied pharmacology, 354, 24-39 (2018-04-08)
Medium- to high-throughput in vitro assays that recapitulate the critical processes of nervous system development have been proposed as a means to facilitate rapid testing and identification of chemicals which may affect brain development. In vivo neurodevelopment is a complex
Wen-jing Xiao et al.
Acta pharmacologica Sinica, 36(2), 259-267 (2015-01-27)
The pentose phosphate pathway (PPP) is involved in the activity of glucose-6-phosphate dehydrogenase (G6PD) and generation of NADPH, which plays a key role in drug metabolism. The aim of this study was to investigate the effects of modulation of the

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